RabMAb

Anti-VAV3 (phospho Y173)抗体[EPR1068A] (ab109544)

概述

  • 产品名称Anti-VAV3 (phospho Y173)抗体[EPR1068A]
    参阅全部 VAV3 一抗
  • 描述
    兔单克隆抗体[EPR1068A] to VAV3 (phospho Y173)
  • 特异性This antibody only detects VAV3 phosphorylated at Tyrosine 173.
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    A phospho specific peptide corresponding to residues surrounding tyrosine 173 of Human VAV3

  • 阳性对照
    • Jurkat cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab109544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 98 kDa.
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
    • 序列相似性Contains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 SH2 domain.
      Contains 2 SH3 domains.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ40431 antibody
      • Guanine nucleotide exchange factor VAV3 antibody
      • Protein vav 3 antibody
      • Protein vav3 antibody
      • RGD1565941 antibody
      • VAV 3 antibody
      • Vav 3 guanine nucleotide exchange factor antibody
      • VAV 3 oncogene antibody
      • VAV 3 protein antibody
      • VAV-3 antibody
      • Vav3 antibody
      • VAV3 oncogene antibody
      • VAV3 protein antibody
      • VAV3_HUMAN antibody
      see all

    Anti-VAV3 (phospho Y173) antibody [EPR1068A] 图像

    • All lanes : Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : Jurkat cell lysate treated with Pervanadate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 98 kDa

    Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544)参考文献

    This product has been referenced in:
    • Kovárová D  et al. Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis. Mol Cancer Res 11:1235-47 (2013). Read more (PubMed: 23938949) »

    See 1 Publication for this product

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    Unfortunately, we do not know of any publications that have used this antibody at the moment. But I would like to reassure you that ab109544 is tested and guaranteed to work in WB with human samples.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"