概述

  • 产品名称Anti-VAV3抗体
    参阅全部 VAV3 一抗
  • 描述
    山羊多克隆抗体to VAV3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rhesus monkey
  • 免疫原

    Synthetic peptide:

    CSGEQGTLKLPEK

    , corresponding to internal sequence amino acids 567-578 of Human VAV3

  • 阳性对照
    • Human Skin Human Spleen Human bone marrow lysate

性能

应用

Our Abpromise guarantee covers the use of ab118904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 98 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
  • 序列相似性Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ40431 antibody
    • Guanine nucleotide exchange factor VAV3 antibody
    • Protein vav 3 antibody
    • Protein vav3 antibody
    • RGD1565941 antibody
    • VAV 3 antibody
    • Vav 3 guanine nucleotide exchange factor antibody
    • VAV 3 oncogene antibody
    • VAV 3 protein antibody
    • VAV-3 antibody
    • Vav3 antibody
    • VAV3 oncogene antibody
    • VAV3 protein antibody
    • VAV3_HUMAN antibody
    see all

Anti-VAV3 antibody 图像

  • Immunohistochemistry analysis (formalin-fixed, paraffin-embedded)of Human Skin stained with ab118904 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Immunohistochemistry analysis (formalin-fixed, paraffin-embedded)of Human Spleen stained with ab118904 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Anti-VAV3 antibody (ab118904) at 0.3 µg/ml + Human bone marrow lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 98 kDa


    Exposure time : 1 hour

Anti-VAV3 antibody (ab118904)参考文献

ab118904 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118904.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"