概述

  • 产品名称
  • 描述
    兔多克隆抗体to VAV2
  • 特异性
    Detects endogenous levels of VAV2 protein.
  • 经测试应用
    适用于: ELISA, WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthesized non phosphopeptide derived from human VAV2 around the phosphorylation site of tyrosine 142 (D-V-YP-R-S).

  • 阳性对照
    • Human brain tissue (IHC), NIH/3T3 cells (WB) and COS7 cells (IF)

性能

应用

Our Abpromise guarantee covers the use of ab79182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
WB 1/500 - 1/1000. Predicted molecular weight: 101 kDa.
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.

靶标

  • 功能
    Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
  • 组织特异性
    Widely expressed.
  • 序列相似性
    Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Guanine nucleotide exchange factor VAV2 antibody
    • Oncogene VAV2 antibody
    • Protein vav 2 antibody
    • VAV 2 antibody
    • Vav 2 oncogene antibody
    • VAV-2 antibody
    • VAV2 antibody
    • VAV2 oncogene antibody
    • VAV2_HUMAN antibody
    see all

图片

  • ab79182, at a dilution of 1/50, staining VAV2 in paraffin embedded human brain tissue by Immunohistochemistry.
    Left image: No peptide. Right image: peptide present.
  • All lanes : Anti-VAV2 antibody (ab79182) at 1/500 dilution

    Lane 1 : Extracts from NIH/3T3 cells
    Lane 2 : Extracts from NIH/3T3 cells with peptide at 10 µg

    Lysates/proteins at 10 µg per lane.


    Predicted band size : 101 kDa
    Observed band size : 101 kDa
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.
  • ab79182, at a dilution of 1/500, staining VAV2 in COS7 cells by Immunofluorescence.
    Left image: No peptide. Right image: peptide present.

文献

ab79182 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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