概述

  • 产品名称Anti-VAV2抗体
    参阅全部 VAV2 一抗
  • 描述
    山羊多克隆抗体to VAV2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide:

    ETEAKYYRTLEDIEC

    , corresponding to Internal sequence amino acids 208-221 of Human VAV2.

  • 常规说明GenBank Accession Number – NP_003362. LocusLink ID - 7410 (human); 22325 (mouse). Gene Ontology terms - guanyl-nucleotide exchange factor activity; intracellular signaling cascade; diacylglycerol binding.

性能

应用

Our Abpromise guarantee covers the use of ab4549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明Peptide ELISA: antibody detection limit dilution >1/32000.
    WB: Use at a concentration of 1 - 1.5 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 100 kDa).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
    • 组织特异性Widely expressed.
    • 序列相似性Contains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 SH2 domain.
      Contains 2 SH3 domains.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Guanine nucleotide exchange factor VAV2 antibody
      • Oncogene VAV2 antibody
      • Protein vav 2 antibody
      • VAV 2 antibody
      • Vav 2 oncogene antibody
      • VAV-2 antibody
      • VAV2 antibody
      • VAV2 oncogene antibody
      • VAV2_HUMAN antibody
      see all

    Anti-VAV2 antibody 图像



    • Predicted band size : 100 kDa


      ab4549 staining (1.5µg/ml) of 293 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

    Anti-VAV2 antibody (ab4549)参考文献

    ab4549 has not yet been referenced specifically in any publications.

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