This antibody detects endogenous levels of total VAV1 protein.
A synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 160
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/1000.
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Widely expressed in hematopoietic cells but not in other cell types.
Contains 1 CH (calponin-homology) domain.
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 SH2 domain.
Contains 2 SH3 domains.
The DH domain is involved in interaction with CCPG1.
Phosphorylated on tyrosine residues.
Information by UniProt
- Oncogene vav antibody
- p95Vav antibody
- Proto-oncogene vav antibody
Immunocytochemistry/ Immunofluorescence - VAV1 antibody (ab62622)
Immunofluorescence analysis of HeLa cells, using ab62622 at a 1:500 dilution.
Left image untreated.
Right image treated with peptide.
has not yet been referenced specifically in any publications.
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