概述

  • 产品名称Anti-VAV1抗体
    参阅全部 VAV1 一抗
  • 描述
    兔多克隆抗体to VAV1
  • 特异性This antibody detects endogenous levels of total VAV1 protein.
  • 经测试应用适用于: ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    A synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 160

  • 阳性对照
    • Hela cells

性能

应用

Our Abpromise guarantee covers the use of ab62622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.

靶标

  • 功能Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
  • 组织特异性Widely expressed in hematopoietic cells but not in other cell types.
  • 序列相似性Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • 结构域The DH domain is involved in interaction with CCPG1.
  • 翻译后修饰Phosphorylated on tyrosine residues.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Oncogene vav antibody
    • p95Vav antibody
    • Proto-oncogene vav antibody
    • Protooncogene vav antibody
    • VAV 1 antibody
    • VAV 1 oncogene antibody
    • VAV antibody
    • Vav proto oncogene antibody
    • VAV_HUMAN antibody
    • VAV1 antibody
    see all

Anti-VAV1 antibody 图像

  • Immunofluorescence analysis of HeLa cells, using ab62622 at a 1:500 dilution.

    Left image untreated.

    Right image treated with peptide.

Anti-VAV1 antibody (ab62622)参考文献

ab62622 has not yet been referenced specifically in any publications.

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