Anti-VANGL2抗体(ab60172)
Key features and details
- Goat polyclonal to VANGL2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-VANGL2抗体
参阅全部 VANGL2 一抗 -
描述
山羊多克隆抗体to VANGL2 -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse
预测可用于: Rat, Xenopus laevis, Zebrafish -
免疫原
Synthetic peptide:
C-QKYLRTTKQQPYH
, corresponding to internal sequence amino acids 403-415 of Human VANGL2 -
阳性对照
- WB: Mouse brain tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab60172于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (1) |
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa).
1 hour primary incubation is recommended for this product. |
说明 |
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WB
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa). 1 hour primary incubation is recommended for this product. |
靶标
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功能
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. -
序列相似性
Belongs to the Vang family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 93840 Mouse
- Entrez Gene: 289229 Rat
- Entrez Gene: 245949 Zebrafish
- SwissProt: Q91ZD4 Mouse
- SwissProt: P84889 Rat
- SwissProt: Q8UVJ6 Zebrafish
- Unigene: 36148 Mouse
- Unigene: 392110 Mouse
see all -
别名
- Homolog of Drosophila strabismus antibody
- KIAA1215 antibody
- Loop tail associated protein antibody
see all
图片
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Anti-VANGL2 antibody (ab60172) at 0.3 µg/ml + Mouse Brain lysate (35µg protein in RIPA buffer)
Predicted band size: 60 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour. Detected by chemiluminescence.
数据表及文件
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Datasheet download
文献 (1)
ab60172 被引用在 1 文献中.
- Li H et al. miR-542-3p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogh-like 2. Mol Med Rep 11:851-6 (2015). WB ; Human . PubMed: 25352048