概述

  • 产品名称Anti-VANGL2抗体
    参阅全部 VANGL2 一抗
  • 描述
    山羊多克隆抗体to VANGL2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide:

    C-QKYLRTTKQQPYH

    , corresponding to internal sequence amino acids 403-415 of Human VANGL2

  • 阳性对照
    • WB: Mouse brain tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab60172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa).

靶标

  • 功能Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.
  • 序列相似性Belongs to the Vang family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Homolog of Drosophila strabismus antibody
    • KIAA1215 antibody
    • Loop tail associated protein antibody
    • loop tail protein 1 homolog antibody
    • Loop-tail protein 1 homolog antibody
    • LPP 1 antibody
    • LPP1 antibody
    • LTAP antibody
    • MGC119403 antibody
    • MGC119404 antibody
    • STB 1 antibody
    • STB1 antibody
    • STBM 1 antibody
    • STBM antibody
    • STBM1 antibody
    • Strabismus 1 antibody
    • van Gogh like protein 2 antibody
    • Van Gogh-like protein 2 antibody
    • Vang (van gogh, Drosophila) like 2 antibody
    • Vang like 2 (van gogh, Drosophila) antibody
    • vang like 2 antibody
    • vang like protein 2 antibody
    • Vang-like protein 2 antibody
    • VANG2_HUMAN antibody
    • VANGL 2 antibody
    • VANGL planar cell polarity protein 2 antibody
    • Vangl2 antibody
    see all

Anti-VANGL2 antibody 图像

Anti-VANGL2 antibody (ab60172)参考文献

This product has been referenced in:
  • Li H  et al. miR-542-3p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogh-like 2. Mol Med Rep 11:851-6 (2015). WB ; Human . Read more (PubMed: 25352048) »

See 1 Publication for this product

Product Wall

Application Western blot
Loading amount 10 µg
Gel Running Conditions Non-reduced Non-Denaturing (Native)
Sample Zebrafish Tissue lysate - whole (whole embryo)
Specification whole embryo
Blocking step BSA as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Abcam user community

Verified customer

提交于 Feb 05 2015

Application Immunohistochemistry (Frozen sections)
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5%
Sample Mouse Tissue sections (Adult Female reproductive - Ovary/Oviduct/Uterus)
Specification Adult Female reproductive - Ovary/Oviduct/Uterus
Permeabilization Yes - PBST (PBS/0.1% v/v TritonX100 (sigma))
Fixative TCA
Username

Ms. Julia Watson

Verified customer

提交于 Nov 24 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"