概述

  • 产品名称
  • 描述
    山羊多克隆抗体to VANGL2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide:

    C-QKYLRTTKQQPYH

    , corresponding to internal sequence amino acids 403-415 of Human VANGL2

  • 阳性对照
    • WB: Mouse brain tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab60172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa).

靶标

  • 功能
    Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.
  • 序列相似性
    Belongs to the Vang family.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Homolog of Drosophila strabismus antibody
    • KIAA1215 antibody
    • Loop tail associated protein antibody
    • loop tail protein 1 homolog antibody
    • Loop-tail protein 1 homolog antibody
    • LPP 1 antibody
    • LPP1 antibody
    • LTAP antibody
    • MGC119403 antibody
    • MGC119404 antibody
    • STB 1 antibody
    • STB1 antibody
    • STBM 1 antibody
    • STBM antibody
    • STBM1 antibody
    • Strabismus 1 antibody
    • van Gogh like protein 2 antibody
    • Van Gogh-like protein 2 antibody
    • Vang (van gogh, Drosophila) like 2 antibody
    • Vang like 2 (van gogh, Drosophila) antibody
    • vang like 2 antibody
    • vang like protein 2 antibody
    • Vang-like protein 2 antibody
    • VANG2_HUMAN antibody
    • VANGL 2 antibody
    • VANGL planar cell polarity protein 2 antibody
    • Vangl2 antibody
    see all

Anti-VANGL2 antibody 图像

实验方案

Anti-VANGL2 antibody (ab60172)参考文献

This product has been referenced in:
  • Li H  et al. miR-542-3p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogh-like 2. Mol Med Rep 11:851-6 (2015). WB ; Human . Read more (PubMed: 25352048) »

See 1 Publication for this product

Product Wall

Application
Western blot
Loading amount
10 µg
Gel Running Conditions
Non-reduced Non-Denaturing (Native)
Sample
Zebrafish Tissue lysate - whole (whole embryo)
Specification
whole embryo
Blocking step
BSA as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Abcam user community

Verified customer

提交于 Feb 05 2015

Application
Immunohistochemistry (Frozen sections)
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5%
Sample
Mouse Tissue sections (Adult Female reproductive - Ovary/Oviduct/Uterus)
Specification
Adult Female reproductive - Ovary/Oviduct/Uterus
Permeabilization
Yes - PBST (PBS/0.1% v/v TritonX100 (sigma))
Fixative
TCA
Username

Ms. Julia Watson

Verified customer

提交于 Nov 24 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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