概述

  • 产品名称
  • 描述
    小鼠多克隆抗体to VAMP8
  • 经测试应用
    适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human)

性能

应用

Our Abpromise guarantee covers the use of ab89158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration. PubMed: 24550300
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 11 kDa.

靶标

  • 功能
    Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.
  • 组织特异性
    Platelets.
  • 序列相似性
    Belongs to the synaptobrevin family.
    Contains 1 v-SNARE coiled-coil homology domain.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EDB antibody
    • Endobrevin antibody
    • VAMP 8 antibody
    • VAMP-8 antibody
    • VAMP8 antibody
    • VAMP8_HUMAN antibody
    • Vesicle associated membrane protein 8 antibody
    • Vesicle-associated membrane protein 8 antibody
    see all

图片

  • Anti-VAMP8 antibody (ab89158) at 1 µg/ml + A431 whole cell lysate (ab7909) at 25 µg

    Predicted band size : 11 kDa
  • Anti-VAMP8 antibody (ab89158) at 1 µg/ml + Transfected 293T lysate at 25 µg

    Predicted band size : 11 kDa
    Observed band size : 11 kDa

文献

This product has been referenced in:
  • Pirooz SD  et al. UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proc Natl Acad Sci U S A 111:2716-21 (2014). WB, ICC/IF ; Human . Read more (PubMed: 24550300) »
  • Messenger SW  et al. Vesicle associated membrane protein 8 (VAMP8)-mediated zymogen granule exocytosis is dependent on endosomal trafficking via the constitutive-like secretory pathway. J Biol Chem 289:28040-53 (2014). Read more (PubMed: 25138214) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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