Anti-Vaccinia Virus抗体(Biotin) (ab21039)

概述

  • 产品名称Anti-Vaccinia Virus抗体(Biotin)
    参阅全部 Vaccinia Virus 一抗
  • 描述
    兔多克隆抗体to Vaccinia Virus (Biotin)
  • 偶联物Biotin
  • 特异性Ab21039 recognizes purified virions and is reactive with Lister, Wyeth, New York City and MVA strains of Vaccinia. Does not react with uninfected cells.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    Does not react with Parainfluenza (1-3), RSV, Adenovirus, Influenza A & B or HSV-1. Not yet tested in other species.
  • 免疫原

    Lister Strain (mixture of virions and infected cell polypeptides).

  • 常规说明

    The antibody is covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 纯度IgG fraction
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab21039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Vaccinia virus is an Orthopoxvirus, containing double stranded DNA. Fusion protein plays an important role in the entry of enveloped virus into cells. As vaccinia virus has a wide host range, it is conceivable that certain cellular components that are ubiquitously expressed on the cell mediate virus infection. The study of the entry process, attachment, fusion and the proteins and receptors involved is complex. During vaccinia virus infection, the fusion process is attributed to the action of the 14KDa protein (A27L). The N terminus of this protein recognises heparan sulfate on the cell surface. It interacts with the negative charges of sulfates of glycosaminoglycans (GAGs). Therefore, antibodies that recognize this 14KDa protein are able to neutralize vaccinia virus infection and enable identification other viral and cellular proteins which participate in the vaccinia virus entry process.
  • 别名
    • A27L antibody
    • Orthopoxvirus antibody

Anti-Vaccinia Virus antibody (Biotin) (ab21039)参考文献

ab21039 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Ab21098 - Mouse monoclonal [TV46] to Vaccinia Virus - reacts with a 27 kDa protein and is weakly reactive with 57 kDa and 6 1kDa proteins in Western blot. The identity of the proteins have not been determined. Ab21039 - ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"