Anti-Vaccinia Virus抗体(ab117453)

概述

  • 产品名称Anti-Vaccinia Virus抗体
    参阅全部 Vaccinia Virus 一抗
  • 描述
    兔多克隆抗体to Vaccinia Virus
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Vaccinia Virus
  • 免疫原

    Lister Strain (mixture of virions and infected cell polypeptides)

性能

应用

Our Abpromise guarantee covers the use of ab117453 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

靶标

  • 相关性Vaccinia virus is an Orthopoxvirus, containing double stranded DNA. Fusion protein plays an important role in the entry of enveloped virus into cells. As vaccinia virus has a wide host range, it is conceivable that certain cellular components that are ubiquitously expressed on the cell mediate virus infection. The study of the entry process, attachment, fusion and the proteins and receptors involved is complex. During vaccinia virus infection, the fusion process is attributed to the action of the 14KDa protein (A27L). The N terminus of this protein recognises heparan sulfate on the cell surface. It interacts with the negative charges of sulfates of glycosaminoglycans (GAGs). Therefore, antibodies that recognize this 14KDa protein are able to neutralize vaccinia virus infection and enable identification other viral and cellular proteins which participate in the vaccinia virus entry process.
  • 别名
    • A27L antibody
    • Orthopoxvirus antibody

Anti-Vaccinia Virus antibody (ab117453)参考文献

ab117453 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (MDA-MB-231 tumor)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Sodium Citrate pH 6
Specification MDA-MB-231 tumor
Blocking step DAKO blocking buffer as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 100% · Temperature: 25°C
Fixative Formaldehyde
Username

Mr. Shyambabu Chaurasiya

Verified customer

提交于 Dec 18 2015


Unfortunately, none of the anti-Vaccinia Virus antibodies we have has been tested for cross-reactivity with Western Reserve Strain.


ab117453 has been tested and cross-reacts with 3 other Vaccinia strains and also with distantly relat...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"