概述

  • 产品名称Anti-UTF1抗体
    参阅全部 UTF1 一抗
  • 描述
    山羊多克隆抗体to UTF1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-PSPPKSADASPAP

    , corresponding to internal sequence amino acids 206-216 of Human UTF1 (NP_003568.2).

  • 阳性对照
    • K562 cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab101033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 37 kDa.

靶标

  • 功能Acts as a transcriptional coactivator of ATF2.
  • 结构域The leucine-zipper domain is required for coactivation activity. When this domain is deleted, the protein is able to stimulate transcription from a number of gene promoters.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 形式UTF1 is a transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells. Upon activation by Oct-3/4, UTF1 may be responsible for the rapid proliferation and tumorigenic properties of embryonic stem cells. Sox2 is also part of the Oct-3/4-containing complex able to bind the regulatory region of UTF1. UTF1 acts as a transcriptional coactivator of ATF2 and it binds to the N-terminal region of ATF2. Associates with the TFIID complex through interaction with TBP.
  • 别名
    • hUTF 1 antibody
    • hUTF1 antibody
    • Undifferentiated embryonic cell transcription factor 1 antibody
    • UTF 1 antibody
    • UTF1 antibody
    • UTF1_HUMAN antibody
    see all

Anti-UTF1 antibody 图像

  • Anti-UTF1 antibody (ab101033) at 1 µg/ml + K562 cell lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 37 kDa

Anti-UTF1 antibody (ab101033)参考文献

ab101033 has not yet been referenced specifically in any publications.

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