概述

  • 产品名称Anti-USP3抗体
    参阅全部 USP3 一抗
  • 描述
    小鼠单克隆抗体to USP3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: RNKVDTYVEF PLRGLDMKCY LLEPENSGPE SCLYDLAAVV VHHGSGVGSG HYTAYATHEG RWFHFNDSTV TLTDEETVVK AKAYILFYVE HQAKAGSDKL , corresponding to amino acids 421-521 of Human USP3

性能

应用

Our Abpromise guarantee covers the use of ab56901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.
    • 组织特异性Expressed in all tissues examined, with strongest expression in pancreas.
    • 序列相似性Belongs to the peptidase C19 family. USP3 subfamily.
      Contains 1 UBP-type zinc finger.
    • 结构域Both protease activity and an intact zinc finger are required for H2A monodeubiquitination.
    • 细胞定位Nucleus. Localizes preferentially with monoubiquitinated H2A to chromatin.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Deubiquitinating enzyme 3 antibody
      • EC 3.1.2.15 antibody
      • SIH003 antibody
      • Ubiquitin carboxyl-terminal hydrolase 3 antibody
      • Ubiquitin specific peptidase 3 antibody
      • Ubiquitin specific processing protease 3 antibody
      • Ubiquitin Specific Protease 3 antibody
      • Ubiquitin thioesterase 3 antibody
      • Ubiquitin thiolesterase 3 antibody
      • Ubiquitin-specific-processing protease 3 antibody
      • UBP antibody
      • UBP3_HUMAN antibody
      • Usp3 antibody
      see all

    Anti-USP3 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56901 USP3 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-USP3 antibody (ab56901)参考文献

    ab56901 has not yet been referenced specifically in any publications.

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