Anti-USP21抗体(ab38864)

概述

  • 产品名称Anti-USP21抗体
    参阅全部 USP21 一抗
  • 描述
    兔多克隆抗体to USP21
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH selected from the C-terminal region of human USP21.

  • 阳性对照
    • Human breast carcinoma tissues.

性能

应用

Our Abpromise guarantee covers the use of ab38864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 63 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
  • 组织特异性Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
  • 序列相似性Belongs to the peptidase C19 family. USP21 subfamily.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Deubiquitinating enzyme 21 antibody
    • deubiquitinating enzyme 23 antibody
    • EC 3.1.2.15 antibody
    • ESTM28 antibody
    • MGC3394 antibody
    • NEDD8-specific protease antibody
    • Ubiquitin carboxyl terminal hydrolase 21 antibody
    • ubiquitin carboxyl terminal hydrolase 23 antibody
    • Ubiquitin carboxyl-terminal hydrolase 21 antibody
    • ubiquitin specific peptidase 21 antibody
    • Ubiquitin specific processing protease 21 antibody
    • ubiquitin specific protease 16 antibody
    • ubiquitin specific protease 21 antibody
    • ubiquitin specific protease 23 antibody
    • Ubiquitin thioesterase 21 antibody
    • Ubiquitin thiolesterase 21 antibody
    • ubiquitin thiolesterase 23 antibody
    • ubiquitin-specific protease 23, formerly antibody
    • Ubiquitin-specific-processing protease 21 antibody
    • UBP21_HUMAN antibody
    • USP16 antibody
    • Usp21 antibody
    • USP23 antibody
    • USP23, formerly antibody
    • W53272 antibody
    see all

Anti-USP21 antibody 图像

  • Anti-USP21 antibody (ab38864) + T47D cell lysate

    Predicted band size : 63 kDa
  • Formalin fixed and paraffin embedded human breast carcinoma tissue stained with ab38864, followed by AEC staining.

Anti-USP21 antibody (ab38864)参考文献

ab38864 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

Your credit note ID for the refundis xxx.

I am sorry that this antibody did not perform as stated on the datasheet, I have asked our Finance department to issue a credit note for you. The credit note m...

Read More

Thank you for your reply and for the additional information that will help us to reevaluate this antibody.

Yes, I'd be happy to compensate you with eithera credit (can be used on future Abcam purchase) or a refund (money back into your accoun...

Read More

Thank you for your email. I am sorry to hear that this antibody is not providing satisfactory results.

Could you please provide the following additional details whichwill enable us to investigate this case and will provide us with vital info...

Read More
Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Loading amount 0.034 µg
Specification Catalytic domain of USP21
Gel Running Conditions Non-reduced Denaturing (12)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 20°C
Sample Human Purified protein (Catalytic domain of USP21)
Username

Mr. Reggy Ekkebus

Verified customer

提交于 Jul 08 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"