概述

  • 产品名称Anti-USP19抗体
    参阅全部 USP19 一抗
  • 描述
    兔多克隆抗体to USP19
  • 特异性USP19 antibody detects endogenous levels of total USP19 protein.
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide derived from an internal region of Human USP19

性能

应用

Our Abpromise guarantee covers the use of ab93159 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
ELISA
  • 应用说明ELISA: 1/20000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 145 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.
    • 序列相似性Belongs to the peptidase C19 family.
      Contains 2 CS domains.
      Contains 1 MYND-type zinc finger.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Endoplasmic reticulum membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 8430421I07Rik antibody
      • AI047774 antibody
      • Deubiquitinating enzyme 19 antibody
      • Ubiquitin carboxyl terminal hydrolase 19 antibody
      • Ubiquitin carboxyl-terminal hydrolase 19 antibody
      • Ubiquitin specific peptidase 19 antibody
      • Ubiquitin specific processing protease 19 antibody
      • Ubiquitin specific protease 19 antibody
      • Ubiquitin thioesterase 19 antibody
      • Ubiquitin thiolesterase 19 antibody
      • Ubiquitin-specific-processing protease 19 antibody
      • UBP19_HUMAN antibody
      • Usp19 antibody
      • Zinc finger MYND domain containing protein 9 antibody
      • Zinc finger MYND domain-containing protein 9 antibody
      • ZMYND9 antibody
      see all

    Anti-USP19 antibody 图像



    • Predicted band size : 145 kDa
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ab93159

    Anti-USP19 antibody (ab93159)参考文献

    This product has been referenced in:
    • Ogawa M  et al. 17ß-estradiol represses myogenic differentiation by increasing ubiquitin-specific peptidase 19 through estrogen receptor a. J Biol Chem 286:41455-65 (2011). WB ; Mouse . Read more (PubMed: 21971047) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"