RabMAb

Anti-Uroplakin III抗体[SP73], prediluted (ab101546)

概述

  • 产品名称Anti-Uroplakin III抗体[SP73], prediluted
    参阅全部 Uroplakin III 一抗
  • 描述
    兔单克隆抗体[SP73] to Uroplakin III, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to C-terminus of Human Uroplakin III

  • 阳性对照
    • Human bladder carcinoma

性能

  • 形式Prediluted
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 1% BSA, 50mM Tris, pH 7.6
  • Concentration information loading...
  • 克隆单克隆
  • 克隆编号SP73
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab101546 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Prediluted and ready to use.

靶标

  • 功能Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
  • 组织特异性Expressed in ureter.
  • 疾病相关Defects in UPK3A are a cause of renal adysplasia (RADYS) [MIM:191830]; also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy.
  • 序列相似性Belongs to the uroplakin-3 family.
  • 细胞定位Endoplasmic reticulum membrane. Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC119178 antibody
    • OTTHUMP00000028951 antibody
    • UP III antibody
    • UP3a antibody
    • UPIII antibody
    • UPIIIA antibody
    • UPK 3 antibody
    • UPK 3A antibody
    • UPK3 antibody
    • UPK3A antibody
    • UPK3A_HUMAN antibody
    • Uroplakin 3A antibody
    • Uroplakin III antibody
    • Uroplakin-3a antibody
    • Uroplakin3A antibody
    • UroplakinIII antibody
    see all

Anti-Uroplakin III antibody [SP73], prediluted 图像

  • ab101546 staining formalin fixed and paraffin embedded Human bladder carcinoma tissue.

Anti-Uroplakin III antibody [SP73], prediluted (ab101546)参考文献

ab101546 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Rat Tissue sections (Urinary bladder cancer)
Specification Urinary bladder cancer
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: 0.01M PH6.0 Citric acid
Permeabilization No
Blocking step “Thermo” UltraVision Quanto Detection System HRP DAB as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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提交于 Jun 16 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"