Anti-Uroplakin III抗体[SFI-1], prediluted (ab78197)

概述

  • 产品名称
    Anti-Uroplakin III抗体[SFI-1], prediluted
    参阅全部 Uroplakin III 一抗
  • 描述
    小鼠单克隆抗体[SFI-1] to Uroplakin III, prediluted
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to an internal region of Human Uroplakin III.

  • 阳性对照
    • Urothelial tissue, bladder.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C. Do Not Freeze.
  • 存储溶液
    Constituents: buffer with carrier protein and preservative.
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    单克隆
  • 克隆编号
    SFI-1
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab78197 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: Ready to use for 30 min at RT. Pre-treatment: Heat Induced Epitope Unmasking in citrate buffer pH 6,0.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
    • 组织特异性
      Expressed in ureter.
    • 疾病相关
      Defects in UPK3A are a cause of renal adysplasia (RADYS) [MIM:191830]; also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy.
    • 序列相似性
      Belongs to the uroplakin-3 family.
    • 细胞定位
      Endoplasmic reticulum membrane. Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
    • Information by UniProt
    • 数据库链接
    • 别名
      • MGC119178 antibody
      • OTTHUMP00000028951 antibody
      • UP III antibody
      • UP3a antibody
      • UPIII antibody
      • UPIIIA antibody
      • UPK 3 antibody
      • UPK 3A antibody
      • UPK3 antibody
      • UPK3A antibody
      • UPK3A_HUMAN antibody
      • Uroplakin 3A antibody
      • Uroplakin III antibody
      • Uroplakin-3a antibody
      • Uroplakin3A antibody
      • UroplakinIII antibody
      see all

    Anti-Uroplakin III antibody [SFI-1], prediluted 图像

    • ab78197 staining Uroplakin III in human bladder by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.
    • ab78197 staining Uroplakin III in mouse bladder tissue sections. Tissue was fixed in formaldehyde and heat-mediated antigen retrieval was performed using citric buffer. Blocking was performed with 1% BSA for 10 minutes at 21ºC and ab78197 was used at 1/30 for 2 hours at 21ºC.

      See Abreview

    • ab78197 staining Uroplakin III in rat bladder tissue sections. Tissue was fixed in formaldehyde and heat-mediated antigen retrieval was performed using citric buffer. Blocking was performed with 1% BSA for 10 minutes at 21ºC and ab78197 was used at 1/30 for 2 hours at 21ºC.

      See Abreview

    Anti-Uroplakin III antibody [SFI-1], prediluted (ab78197)参考文献

    ab78197 has not yet been referenced specifically in any publications.

    Product Wall

    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Blocking step
    BSA as blocking agent for 10 minute(s) · Concentration: 1% · Temperature: 21°C
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: Citric acid
    Sample
    Mouse Tissue sections (Urinary bladder)
    Specification
    Urinary bladder
    Permeabilization
    No
    Fixative
    Formaldehyde
    Username

    Mr. Carl Hobbs

    Verified customer

    提交于 Aug 10 2014

    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Blocking step
    BSA as blocking agent for 10 minute(s) · Concentration: 1% · Temperature: 21°C
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: Citric acid
    Sample
    Rat Tissue sections (Urinary bladder)
    Specification
    Urinary bladder
    Permeabilization
    No
    Fixative
    Formaldehyde
    Username

    Mr. Carl Hobbs

    Verified customer

    提交于 Aug 10 2014

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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