概述
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产品名称Anti-Urokinase抗体(Biotin)
参阅全部 Urokinase 一抗 -
描述兔多克隆抗体to Urokinase (Biotin)
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宿主Rabbit
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偶联物Biotin
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经测试应用适用于: ELISA, RIA, IP, WBmore details
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种属反应性与反应: Human
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免疫原
Full length native ATF uPA purified from plasma (Human)
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常规说明
ATF is the amino terminal fragment of urokinase (uPA) corresponding to amino acid residues 1-135. uPA-ATF contains the growth factor like domain, which binds to the urokinase receptor, and the kringle domain which is involved in the induction of cell chemotaxis by urokinase. ATF inhibits the binding of urokinase to its receptor uPAR and acts as a broad inhibitor of cell migration.
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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存储溶液Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 50% Glycerol, PBS, pH 7.5 -
Concentration information loading... -
纯度Protein G purified
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Primary antibody说明ATF is the amino terminal fragment of urokinase (uPA) corresponding to amino acid residues 1-135. uPA-ATF contains the growth factor like domain, which binds to the urokinase receptor, and the kringle domain which is involved in the induction of cell chemotaxis by urokinase. ATF inhibits the binding of urokinase to its receptor uPAR and acts as a broad inhibitor of cell migration.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab49577 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA | Use at an assay dependent dilution. | |
| RIA | Use at an assay dependent dilution. | |
| IP | Use at an assay dependent dilution. | |
| WB | Use at an assay dependent dilution. Detects a band of approximately N\A kDa. |
靶标
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功能Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
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组织特异性Expressed in the prostate gland and prostate cancers.
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序列相似性Belongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain. -
翻译后修饰Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
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细胞定位Secreted.
- Information by UniProt
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数据库链接
- Entrez Gene: 5328 Human
- Omim: 191840 Human
- SwissProt: P00749 Human
- Unigene: 77274 Human
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别名
- ATF antibody
- ATF uPA antibody
- BDPLT5 antibody
see all
文献
ab49577 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"