Anti-Urokinase抗体(Biotin) (ab49577)

概述

  • 产品名称Anti-Urokinase抗体(Biotin)
    参阅全部 Urokinase 一抗
  • 描述
    兔多克隆抗体to Urokinase (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: ELISA, RIA, IP, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native ATF uPA purified from plasma (Human)

  • 常规说明


    ATF is the amino terminal fragment of urokinase (uPA) corresponding to amino acid residues 1-135. uPA-ATF contains the growth factor like domain, which binds to the urokinase receptor, and the kringle domain which is involved in the induction of cell chemotaxis by urokinase. ATF inhibits the binding of urokinase to its receptor uPAR and acts as a broad inhibitor of cell migration.

性能

应用

Our Abpromise guarantee covers the use of ab49577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.
IP Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately N\A kDa.

靶标

  • 功能Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • 组织特异性Expressed in the prostate gland and prostate cancers.
  • 序列相似性Belongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • 翻译后修饰Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATF antibody
    • ATF uPA antibody
    • BDPLT5 antibody
    • Plasminogen activator antibody
    • Plasminogen activator urinary antibody
    • Plasminogen activator urokinase antibody
    • PLAU antibody
    • QPD antibody
    • u PA antibody
    • U plasminogen activator antibody
    • u-PA antibody
    • U-plasminogen activator antibody
    • uPA antibody
    • URK antibody
    • UROK_HUMAN antibody
    • Urokinase plasminogen activator antibody
    • Urokinase type plasminogen activator antibody
    • Urokinase type plasminogen activator precursor antibody
    • Urokinase-type plasminogen activator chain B antibody
    see all

Anti-Urokinase antibody (Biotin) (ab49577)参考文献

ab49577 has not yet been referenced specifically in any publications.

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