Anti-Urocortin 3抗体(ab77433)
Key features and details
- Goat polyclonal to Urocortin 3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Urocortin 3抗体
参阅全部 Urocortin 3 一抗 -
描述
山羊多克隆抗体to Urocortin 3 -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide with sequence
KPRQDTAKSPHRTK
, from the internal region of the human protein Urocortin 3 (NP_444277.2) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab77433 is purified by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab77433于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 18 kDa).
A 1 hour primary incubation is recommended for this product. |
说明 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 18 kDa). A 1 hour primary incubation is recommended for this product. |
靶标
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相关性
Urocortin 3 is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. A powerful cytoprotective effect of urocortin peptide administration against ischemia and reperfusion injury has been demonstrated in isolated cardiomyocyte models, as well as in the intact heart both in vitro and in vivo. -
细胞定位
Secreted -
数据库链接
- Entrez Gene: 114131 Human
- Omim: 605901 Human
- SwissProt: Q969E3 Human
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别名
- MGC119002 antibody
- OTTHUMP00000018999 antibody
- Prepro urocortin 3 antibody
see all
图片
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Lanes 1-2 : Anti-Urocortin 3 antibody (ab77433) at 1 µg/ml
Lane 3 : Anti DYKDDDDK-Tag antibody at 1/3000 dilution
Lane 1 : HEK293 cell lysate overexpressing Urocortin 3 with DYKDDDDK tag at 10 µg
Lane 2 : Mock-transfected HEK293 cell
Lane 3 : HEK293 cell lysate overexpressing Urocortin 3 with DYKDDDDK tag at 35 µg
Developed using the ECL technique.
Predicted band size: 18 kDa
Observed band size: 19 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (0)
ab77433 尚未被引用在任何文献中。