This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Anti-UPF3B/RENT3B抗体(ab42731)

概述

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

  • 应用说明This antibody gave a positive result in ELISA against the immunizing peptide (ab45333).
    Not yet tested in other applications.
  • 靶标

    • 相关性UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. UPF3B binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X (referenced from entrez gene).
    • 细胞定位Nucleus. Cytoplasm. Note: Shuttling between the nucleus and the cytoplasm.
    • 数据库链接
    • 别名
      • HUPF3B antibody
      • hUpf3p X antibody
      • MRXS14 antibody
      • Nonsense mRNA reducing factor 3B antibody
      • Regulator of nonsense transcripts 3B antibody
      • RENT3B antibody
      • Up-frameshift suppressor 3 homolog B antibody
      • Up-frameshift suppressor 3 homolog on chromosome X antibody
      • UPF3 regulator of nonsense transcripts homolog B (yeast) antibody
      • UPF3 regulator of nonsense transcripts homolog B antibody
      • UPF3B antibody
      • UPF3X antibody
      see all

    Anti-UPF3B/RENT3B antibody (ab42731)参考文献

    ab42731 has not yet been referenced specifically in any publications.

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