概述

  • 产品名称Anti-UPF3A抗体
    参阅全部 UPF3A 一抗
  • 描述
    小鼠多克隆抗体to UPF3A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human UPF3A, (NP_542418.1, 443 a.a)

  • 阳性对照
    • UPF3A transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab68777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight for shorter isoform : 51 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon junctions.
    • 组织特异性Isoform 1 is strongly expressed in testis, uterus, muscle, fetal brain and spinal cord. Isoform 2 is strongly expressed in fetal brain and spinal cord.
    • 序列相似性Belongs to the RENT3 family.
    • 细胞定位Nucleus. Cytoplasm. Shuttling between the nucleus and the cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 2600001C03Rik antibody
      • 4930546M19Rik antibody
      • hUpf3 antibody
      • HUPF3A antibody
      • MGC151365 antibody
      • Nonsense mRNA reducing factor 3A antibody
      • OTTHUMP00000018789 antibody
      • Regulator of nonsense transcripts 3A antibody
      • REN3A_HUMAN antibody
      • RENT3A antibody
      • Up frameshift suppressor 3 homolog A antibody
      • Up-frameshift suppressor 3 homolog A antibody
      • UPF3 A antibody
      • UPF3 antibody
      • UPF3 regulator of nonsense transcripts homolog A antibody
      • upf3a antibody
      see all

    Anti-UPF3A antibody 图像

    • All lanes : Anti-UPF3A antibody (ab68777) at 1/500 dilution

      Lane 1 : UPF3A transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 51 kDa
      Observed band size : 70 kDa (why is the actual band size different from the predicted?)

    Anti-UPF3A antibody (ab68777)参考文献

    ab68777 has not yet been referenced specifically in any publications.

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