概述

  • 产品名称Anti-uPA Receptor抗体
    参阅全部 uPA Receptor 一抗
  • 描述
    山羊多克隆抗体to uPA Receptor
  • 经测试应用适用于: WB, IP, Neutralisingmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human).

性能

应用

Our Abpromise guarantee covers the use of ab3129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 55 kDa.
IP Use a concentration of 5 - 10 µg/ml.
Neutralising Use a concentration of 2 - 4 µg/ml.

靶标

  • 功能Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
  • 组织特异性Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
  • 序列相似性Contains 3 UPAR/Ly6 domains.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 87 antibody
    • CD87 antibody
    • CD87 antigen antibody
    • MO 3 antibody
    • MO3 antibody
    • Monocyte activation antigen Mo3 antibody
    • Plasminogen activator receptor urokinase antibody
    • Plasminogen activator urokinase receptor antibody
    • PLAUR antibody
    • U PAR antibody
    • u plasminogen activator receptor antibody
    • U-PAR antibody
    • u-plasminogen activator receptor form 2 antibody
    • UPA receptor antibody
    • uPAR antibody
    • UPAR_HUMAN antibody
    • Urinary plasminogen activator receptor antibody
    • URKR antibody
    • Urokinase plasminogen activator receptor antibody
    • Urokinase plasminogen activator surface receptor antibody
    • urokinase-type plasminogen activator (uPA) receptor antibody
    see all

Anti-uPA Receptor antibody (ab3129)参考文献

This product has been referenced in:
  • Al-Souhibani N  et al. The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. Oncogene : (2010). WB ; Human . Read more (PubMed: 20498646) »
  • Bezuidenhout L  et al. Ang-2 and PDGF-BB cooperatively stimulate human peripheral blood monocyte fibrinolysis. J Leukoc Biol 81:1496-503 (2007). Neutralising ; Human . Read more (PubMed: 17395886) »

See all 2 Publications for this product

Product Wall

Thank you for your email. The lot number customer used in 2007 was different than you have been using. So we would expect some variations due to cell line or other lab related factors. I can assure you that there is no change in the antibody its...

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Thank you for contacting us. Could you specify are the cells just dying or there is some kind of fungus or bacterial growth? The antibody solution only contain sodium azide as cytotoxic compound however the affect of this would be minimal at th...

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Thank you for your enquiry. Ab3129 has not yet been tested for cross-reactivity with mouse uPA, so I would suggest a control from human samples. For example, uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells. If yo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"