概述

  • 产品名称
  • 描述
    兔多克隆抗体to Unrip
  • 经测试应用
    适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    A region within synthetic peptide: LRLWQTVVGK TYGLWKCVLP EEDSGELAKP KIGFPETTEE ELEEIASENS, corresponding to C terminal amino acids 289-338 of Human Unrip

  • 阳性对照
    • HepG2 cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab64424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
  • 序列相似性
    Belongs to the WD repeat STRAP family.
    Contains 7 WD repeats.
  • 细胞定位
    Cytoplasm. Nucleus. Localized predominantly in the cytoplasm but also found in the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MAP activator with WD repeats antibody
    • MAWD antibody
    • PTWD antibody
    • Serine-threonine kinase receptor-associated protein antibody
    • serine/threonine kinase receptor associated protein antibody
    • strap antibody
    • STRAP_HUMAN antibody
    • UNR-interacting protein antibody
    • UNRIP antibody
    • WD 40 repeat protein PT WD antibody
    • WD-40 repeat protein PT-WD antibody
    see all

Anti-Unrip antibody 图像

  • Anti-Unrip antibody (ab64424) at 2.5 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 39 kDa
    Observed band size : 39 kDa

Anti-Unrip antibody (ab64424)参考文献

ab64424 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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