Recombinant Protein Epitope Signature Tag antigen: VLDELSVTYG ESFQVIIEEC IKQMSFELNQ MRANGNTTSN KNSAAMDAEI V, corresponding to amino acids 1838 - 1888 of Human UNC13C (Q8NB66).
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Probably plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Probably is involved in neurotransmitter release.
Exclusively expressed in brain.
Belongs to the unc-13 family.
Contains 2 C2 domains.
Contains 1 MHD1 (MUNC13 homology domain 1) domain.
Contains 1 MHD2 (MUNC13 homology domain 2) domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
The C2 domains are not involved in calcium-dependent phospholipid binding.
Cytoplasm. Membrane. Cell junction > synapse > presynaptic cell membrane. Localized to presynaptic structures.
Information by UniProt
- DKFZp547H074 antibody
- Munc13 3 antibody
- Munc13-3 antibody
Anti-UNC13C antibody (ab122725)参考文献
has not yet been referenced specifically in any publications.
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