Anti-UNC13C抗体(ab122725)

概述

  • 产品名称Anti-UNC13C抗体
  • 描述
    兔多克隆抗体to UNC13C
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant Protein Epitope Signature Tag antigen: VLDELSVTYG ESFQVIIEEC IKQMSFELNQ MRANGNTTSN KNSAAMDAEI V, corresponding to amino acids 1838 - 1888 of Human UNC13C (Q8NB66).

  • 阳性对照
    • Human testis tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab122725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Probably plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Probably is involved in neurotransmitter release.
  • 组织特异性Exclusively expressed in brain.
  • 序列相似性Belongs to the unc-13 family.
    Contains 2 C2 domains.
    Contains 1 MHD1 (MUNC13 homology domain 1) domain.
    Contains 1 MHD2 (MUNC13 homology domain 2) domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
  • 结构域The C2 domains are not involved in calcium-dependent phospholipid binding.
  • 细胞定位Cytoplasm. Membrane. Cell junction > synapse > presynaptic cell membrane. Localized to presynaptic structures.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp547H074 antibody
    • Munc13 3 antibody
    • Munc13-3 antibody
    • Protein unc-13 homolog C antibody
    • UN13C_HUMAN antibody
    • Unc13c antibody
    see all

Anti-UNC13C antibody 图像

  • ab122725, at 1/20 diltuion, staining UNC13C in paraffin-embedded Human testis tissue by Immunohistochemistry.

Anti-UNC13C antibody (ab122725)参考文献

ab122725 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - other (whole brain)
Loading amount 100 µg
Specification whole brain
Gel Running Conditions Reduced Denaturing (3.5% stacking gel, 7.5% running gel)
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 2% · Temperature: 25°C
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提交于 Dec 21 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"