概述

  • 产品名称Anti-UMPS抗体
    参阅全部 UMPS 一抗
  • 描述
    小鼠单克隆抗体to UMPS
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: DYTRAAVRMA EEHSEFVVGF ISGSRVSMKP EFLHLTPGVQ LEAGGDNLGQ QYNSPQEVIG KRGSDIIIVG RGIISAADRL EAAEMYRKAA WEAYLSRLG, corresponding to amino acids 381-480 of Human UMPS

性能

应用

Our Abpromise guarantee covers the use of ab58082 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 通路Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.
      Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.
    • 疾病相关Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:258900]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.
    • 序列相似性In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
      In the C-terminal section; belongs to the OMP decarboxylase family.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ODC antibody
      • OMPdecase antibody
      • OPRT antibody
      • OPRTase antibody
      • Orotate phosphoribosyl transferase and orotidine 5' decarboxylase antibody
      • Orotate phosphoribosyltransferase antibody
      • Orotate phosphoribosyltransferase phosphoribosyltransferase antibody
      • Orotidine 5' phosphate decarboxylase antibody
      • Orotidine 5''-phosphate decarboxylase antibody
      • RP11-71H17.9 antibody
      • UMP synthase antibody
      • Umps antibody
      • UMPS_HUMAN antibody
      • Uridine 5' monophosphate synthase antibody
      • Uridine monophosphate synthetase antibody
      see all

    Anti-UMPS antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab58082 UMPS antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-UMPS antibody (ab58082)参考文献

    ab58082 has not yet been referenced specifically in any publications.

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