RabMAb

Anti-UGGT抗体[EPR5105] (ab124879)

概述

  • 产品名称Anti-UGGT抗体[EPR5105]
    参阅全部 UGGT 一抗
  • 描述
    兔单克隆抗体[EPR5105] to UGGT
  • 经测试应用适用于: WB, IHC-Pmore details
    不适用于: Flow Cyt,ICC or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human UGGT (Q9NYU2).

  • 阳性对照
    • Human skeletal muscle, BXPC-3, SH-SY5Y, and MCF7 lysates, Human brain tissue
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EPR5105
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab124879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/10000 - 1/50000. Detects a band of approximately 170 kDa (predicted molecular weight: 177 kDa).
IHC-P 1/100 - 1/250.
  • 应用说明Is unsuitable for Flow Cyt,ICC or IP.
  • 靶标

    • 功能Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
    • 组织特异性Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
    • 通路Protein modification; protein glycosylation.
    • 序列相似性Belongs to the glycosyltransferase 8 family.
    • 结构域The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
    • 细胞定位Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
    • Information by UniProt
    • 数据库链接
    • 别名
      • GT antibody
      • HUGT1 antibody
      • UDP glucose glycoprotein glucosyltransferase 1 antibody
      • UDP Glucose Glycoprotein Glucosyltransferase antibody
      • UDP--Glc:glycoprotein glucosyltransferase antibody
      • UDP-glucose ceramide glucosyltransferase-like 1 antibody
      • UDP-glucose:glycoprotein glucosyltransferase 1 antibody
      • UGCGL1 antibody
      • UGGG1 antibody
      • UGGG1_HUMAN antibody
      • UGGT antibody
      • Uggt1 antibody
      • UGT1 antibody
      • UGTR antibody
      see all

    Anti-UGGT antibody [EPR5105] 图像

    • All lanes : Anti-UGGT antibody [EPR5105] (ab124879) at 1/10000 dilution

      Lane 1 : Human skeletal muscle lysate
      Lane 2 : BXPC-3 cell lysate
      Lane 3 : SH-SY5Y cell lysate
      Lane 4 : MCF7 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 177 kDa
    • Staining of UGGT in Paraffin-embedded Human brain tissue by Immunohistochemistry using ab124879 at a dilution of 1/100.

    Anti-UGGT antibody [EPR5105] (ab124879)参考文献

    ab124879 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab124879.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"