概述

  • 产品名称
  • 描述
    兔多克隆抗体to UGGT
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    EEKELGTLHEEETQE

    , corresponding to amino acids 1505-1519 of Rat UGGT.

  • 阳性对照
    • Rat Brain Tissue Extract.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: None
    Constituents: Whole Serum
  • 纯度
    Whole antiserum
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab13520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 170 kDa (predicted molecular weight: 170 kDa).

靶标

  • 功能
    Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
  • 组织特异性
    Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
  • 通路
    Protein modification; protein glycosylation.
  • 序列相似性
    Belongs to the glycosyltransferase 8 family.
  • 结构域
    The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
  • 细胞定位
    Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GT antibody
    • HUGT1 antibody
    • UDP glucose glycoprotein glucosyltransferase 1 antibody
    • UDP Glucose Glycoprotein Glucosyltransferase antibody
    • UDP--Glc:glycoprotein glucosyltransferase antibody
    • UDP-glucose ceramide glucosyltransferase-like 1 antibody
    • UDP-glucose:glycoprotein glucosyltransferase 1 antibody
    • UGCGL1 antibody
    • UGGG1 antibody
    • UGGG1_HUMAN antibody
    • UGGT antibody
    • Uggt1 antibody
    • UGT1 antibody
    • UGTR antibody
    see all

图片

  • Western blot analysis of rat brain tissue extract.

实验方案

文献

ab13520 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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