概述

  • 产品名称Anti-UGGT抗体
    参阅全部 UGGT 一抗
  • 描述
    兔多克隆抗体to UGGT
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 1481-1530 (AAVRIVPEWQ DYDQEIKQLQ IRFQKEKETG ALYKEKTKEP SREGPQKREE) of Human UGGT (NP_001020948.1).

  • 阳性对照
    • HepG2 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab105704 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 175 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
  • 组织特异性Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
  • 通路Protein modification; protein glycosylation.
  • 序列相似性Belongs to the glycosyltransferase 8 family.
  • 结构域The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
  • 细胞定位Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GT antibody
    • HUGT1 antibody
    • UDP glucose glycoprotein glucosyltransferase 1 antibody
    • UDP Glucose Glycoprotein Glucosyltransferase antibody
    • UDP--Glc:glycoprotein glucosyltransferase antibody
    • UDP-glucose ceramide glucosyltransferase-like 1 antibody
    • UDP-glucose:glycoprotein glucosyltransferase 1 antibody
    • UGCGL1 antibody
    • UGGG1 antibody
    • UGGG1_HUMAN antibody
    • UGGT antibody
    • Uggt1 antibody
    • UGT1 antibody
    • UGTR antibody
    see all

Anti-UGGT antibody 图像

  • Anti-UGGT antibody (ab105704) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 175 kDa

Anti-UGGT antibody (ab105704)参考文献

ab105704 has not yet been referenced specifically in any publications.

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