Anti-UCKL1抗体- N-terminal (ab71501)

概述

  • 产品名称Anti-UCKL1抗体- N-terminal
    参阅全部 UCKL1 一抗
  • 描述
    兔多克隆抗体to UCKL1 - N-terminal
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the N-terminal region of human UCKL1, conjugated to KLH.

  • 阳性对照
    • 293 cell lysate. Human hepatocarcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Ammonium Sulphate Precipitation
  • 纯化说明ab71501 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab71501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).
IHC-P 1/50 - 1/100.
ELISA 1/1000.

靶标

  • 功能May contribute to UTP accumulation needed for blast transformation and proliferation.
  • 组织特异性Ubiquitous.
  • 通路Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.
    Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.
  • 序列相似性Belongs to the uridine kinase family.
  • 翻译后修饰Ubiquitinated by RNF19B; which induces proteasomal degradation.
  • 细胞定位Cytoplasm. Nucleus. EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
  • Information by UniProt
  • 数据库链接
  • 别名
    • F538 antibody
    • UCK 1L antibody
    • UCK1 like antibody
    • UCK1L antibody
    • UCKL 1 antibody
    • UCKL1 antibody
    • UCKL1_HUMAN antibody
    • Uridine cytidine kinase 1 like 1 antibody
    • Uridine kinase like 1 antibody
    • Uridine-cytidine kinase-like 1 antibody
    • Uridine/cytidine kinase like 1 antibody
    • URKL 1 antibody
    • URKL1 antibody
    see all

Anti-UCKL1 antibody - N-terminal 图像

  • Anti-UCKL1 antibody - N-terminal (ab71501) at 1/50 dilution + 293 cell lysate at 35 µg

    Predicted band size : 61 kDa
    Observed band size : 61 kDa
    Additional bands at : 54 kDa. We are unsure as to the identity of these extra bands.
  • ab71501 at 1/50 dilution, staining UCKL1 in human hepatocarcinoma by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining

Anti-UCKL1 antibody - N-terminal (ab71501)参考文献

ab71501 has not yet been referenced specifically in any publications.

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