概述

  • 产品名称
  • 描述
    兔多克隆抗体to UCH37
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to N terminal of UCH37 and derived from within residues 1-100 (Human)

  • 阳性对照
    • Mouse kidney tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab38528 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).

靶标

  • 功能
    Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome.
  • 序列相似性
    Belongs to the peptidase C12 family.
  • 细胞定位
    Cytoplasm. Nucleus. Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • UCH37 antibody
    • AD-019 antibody
    • CGI 70 antibody
    • INO80 complex subunit R antibody
    • INO80R antibody
    • Ubiquitin C terminal hydrolase L5 antibody
    • Ubiquitin C terminal hydrolase UCH37 antibody
    • Ubiquitin C-terminal hydrolase UCH37 antibody
    • Ubiquitin carboxyl terminal esterase L5 antibody
    • Ubiquitin carboxyl terminal hydrolase isozyme L5 antibody
    • Ubiquitin carboxyl terminal hydrolase L5 antibody
    • Ubiquitin carboxyl-terminal hydrolase isozyme L5 antibody
    • Ubiquitin thioesterase L5 antibody
    • Ubiquitin thiolesterase L5 antibody
    • UCH L5 antibody
    • UCH-L5 antibody
    • UCHL5 antibody
    • UCHL5_HUMAN antibody
    see all

Anti-UCH37 antibody 图像

  • Anti-UCH37 antibody (ab38528) + mouse kidney tissue lysate

    Predicted band size : 38 kDa
    Observed band size : 38 kDa
    Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.

实验方案

Anti-UCH37 antibody (ab38528)参考文献

This product has been referenced in:
  • Mahanic CS  et al. Regulation of E2 promoter binding factor 1 (E2F1) transcriptional activity through a deubiquitinating enzyme, UCH37. J Biol Chem 290:26508-22 (2015). Read more (PubMed: 26396186) »
  • Chen PC  et al. Ubiquitin homeostasis is critical for synaptic development and function. J Neurosci 31:17505-13 (2011). Read more (PubMed: 22131412) »

See all 4 Publications for this product

Product Wall

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement for one vial of ab21941.  To check the status of the order please contact our Custome...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册