Anti-UBXN6抗体[2F8-24] (ab81555)

概述

  • 产品名称Anti-UBXN6抗体[2F8-24]
    参阅全部 UBXN6 一抗
  • 描述
    小鼠单克隆抗体[2F8-24] to UBXN6
  • 特异性Only detects the full-length isoform.
  • 经测试应用适用于: WB, IP, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length Human protein

  • 阳性对照
    • U20S cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, 0.5% PBS, 0.1% BSA
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号2F8-24
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab81555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa.
IP Use at 1-2 - 0.5 µg/mg of lysate.
ICC/IF Use a concentration of 0.05 - 0.5 µg/ml.

靶标

  • 功能Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation.
  • 组织特异性Enhanced expression in testis.
  • 序列相似性Contains 1 PUB (PUG) domain.
    Contains 1 UBX domain.
  • 结构域The UBX domain lacks key residues critical for VCP binding.
  • 细胞定位Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes at the centrosome both in interphase and during mitosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • UBX domain containing 1 antibody
    • UBX domain containing 2 antibody
    • UBX domain containing protein 1 antibody
    • UBX domain containing protein 6 antibody
    • UBX domain protein 6 antibody
    • UBX domain-containing protein 1 antibody
    • UBX domain-containing protein 6 antibody
    • UBXD1 antibody
    • UBXDC2 antibody
    • Ubxn6 antibody
    • UBXN6_HUMAN antibody
    see all

Anti-UBXN6 antibody [2F8-24] 图像

  • All lanes : Anti-UBXN6 antibody [2F8-24] (ab81555) at 1 µg/ml

    Lane 1 : U20S cells transfected with UBXN6 shRNA
    Lane 2 : U20S cells transfected with mismatch control shRNA


    Predicted band size : 50 kDa
    Observed band size : 54 kDa (why is the actual band size different from the predicted?)

Anti-UBXN6 antibody [2F8-24] (ab81555)参考文献

ab81555 has not yet been referenced specifically in any publications.

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