概述

  • 产品名称Anti-UBXD2抗体
  • 描述
    兔多克隆抗体to UBXD2
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide: RLPDGSSFTN QFPSDAPLEE ARQFAAQTVG NTYGNFSLAT MFPRREFTKE, corresponding to a region within internal sequence amino acids 325-374 of Human UBXD2

  • 阳性对照
    • HepG2 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab66010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 4 - 8 µg/ml.
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP) and promotes ER-associated protein degradation (ERAD). Immunohistochemical staining of brain tissue from patients with Alzheimer's disease and control subjects revealed that UBXD2 accumulates preferentially in neurons undergoing neurofibrillary degeneration in Alzheimer's disease.
  • 细胞定位Endoplasmic reticulum membrane. Both the N- and the C-terminus face the cytosol; also found in the nucleus envelope contiguous to the ER.
  • 数据库链接
  • 别名
    • Erasin antibody
    • FLJ23318 antibody
    • KIAA0242 antibody
    • KIAA2042 antibody
    • UBX domain containing 1 antibody
    • UBX domain containing 2 antibody
    • UBX domain containing protein 2 antibody
    • UBXD 2 antibody
    • UBXDC 1 antibody
    • UBXDC1 antibody
    see all

Anti-UBXD2 antibody 图像

  • Anti-UBXD2 antibody (ab66010) at 2.5 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
  • ab66010 at 8 µg/ml staining UBXD2 in Human kidney tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

Anti-UBXD2 antibody (ab66010)参考文献

ab66010 has not yet been referenced specifically in any publications.

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