Anti-Ubiquinol-Cytochrome C Reductase Core蛋白I抗体(ab96333)
Key features and details
- Rabbit polyclonal to Ubiquinol-Cytochrome C Reductase Core Protein I
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
-
产品名称
Anti-Ubiquinol-Cytochrome C Reductase Core蛋白I抗体
参阅全部 Ubiquinol-Cytochrome C Reductase Core Protein I 一抗 -
描述
兔多克隆抗体to Ubiquinol-Cytochrome C Reductase Core蛋白I -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat, Cow, Monkey -
免疫原
Recombinant fragment, corresponding to a region within amino acids 1-176 of Human Ubiquinol-Cytochrome C Reductase Core Protein I (NP_003356)
-
阳性对照
- HepG2 whole cell lysate (ab7900) and 293T cell lysate
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96333于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 53 kDa.
|
|
IHC-P |
1/100 - 1/1000.
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 53 kDa. |
IHC-P
1/100 - 1/1000. |
靶标
-
功能
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. -
序列相似性
Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily. -
细胞定位
Mitochondrion inner membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 282393 Cow
- Entrez Gene: 7384 Human
- Entrez Gene: 22273 Mouse
- Entrez Gene: 301011 Rat
- Omim: 191328 Human
- SwissProt: P31800 Cow
- SwissProt: P31930 Human
- SwissProt: Q8K2S8 Mouse
see all -
别名
- Complex III subunit 1 antibody
- Core protein I antibody
- Cytochrome b c1 complex subunit 1, mitochondrial antibody
see all
图片
-
Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody (ab96333) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 53 kDa
7.5% SDS PAGE -
Immunohistochemical analysis of PFA fixed, paraffin-embedded mouse liver tissue labeling Ubiquinol-Cytochrome C Reductase Core Protein 1 with ab96333 at 1/500 dilution.
数据表及文件
-
SDS download
-
Datasheet download
文献 (5)
ab96333 被引用在 5 文献中.
- Shan W et al. Critical role of UQCRC1 in embryo survival, brain ischemic tolerance and normal cognition in mice. Cell Mol Life Sci 76:1381-1396 (2019). PubMed: 30666338
- Alberdi P et al. The redox metabolic pathways function to limit Anaplasma phagocytophilum infection and multiplication while preserving fitness in tick vector cells. Sci Rep 9:13236 (2019). PubMed: 31520000
- Reyes A et al. RNase H1 Regulates Mitochondrial Transcription and Translation via the Degradation of 7S RNA. Front Genet 10:1393 (2019). PubMed: 32082360
- Peng X et al. Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-a-mediated signaling. Cell Death Dis 5:e1367 (2014). WB ; Human . PubMed: 25118927
- Chen X et al. Identification of differentially expressed proteins between bull X and Y spermatozoa. J Proteomics : (2012). WB . PubMed: 22820535