Anti-UBE4B抗体(ab97697)

概述

  • 产品名称Anti-UBE4B抗体
    参阅全部 UBE4B 一抗
  • 描述
    兔多克隆抗体to UBE4B
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Zebrafish
  • 免疫原

    Recombinant fragment containing a sequence corresponding to a region within amino acids 740-1020 of Human UBE4B (NP_006039).

  • 阳性对照
    • HepG2 whole cell lysate; CA922 xenograft; 293T, A431, H1299, HeLa, Molt-4 and Raji cell lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab97697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: Isoform 2, 133 ; Isoform 1, 146 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3.
  • 组织特异性Highest expression in ovary, testis, heart and skeletal muscle. Expression is low in colon, thymus and peripheral blood leukocytes. Almost undetectable in lung and spleen.
  • 序列相似性Belongs to the ubiquitin conjugation factor E4 family.
    Contains 1 U-box domain.
  • 翻译后修饰Proteolytically cleaved by caspases during apoptosis. Cleaved efficiently at Asp-123 by caspase-6 and granzyme B. Cleaved with approximately 10-fold less efficiency at Asp-109 by caspase-3 and caspase-7.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4930551I19Rik antibody
    • 4933406G05Rik antibody
    • AU014668 antibody
    • D4Bwg0973e antibody
    • E4 antibody
    • HDNB1 antibody
    • Homozygously deleted in neuroblastoma 1 antibody
    • KIAA0684 antibody
    • mKIAA0684 antibody
    • RP23 173D8.1 antibody
    • Ube4b antibody
    • UBE4B_HUMAN antibody
    • Ubiquitin conjugation factor E4 B antibody
    • Ubiquitin fusion degradation protein 2 antibody
    • UBOX3 antibody
    • UFD2 antibody
    • UFD2a antibody
    • Ufd2p antibody
    see all

Anti-UBE4B antibody 图像

  • Anti-UBE4B antibody (ab97697) at 1/10000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : Isoform 2, 133 ; Isoform 1, 146 kDa
  • Immunohistochemical analysis of UBE4B in paraffin-embedded CA922 xenograft, using ab97697 at 1/500 dilution.

Anti-UBE4B antibody (ab97697)参考文献

ab97697 has not yet been referenced specifically in any publications.

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