Anti-Ube2L3抗体- N-terminal (ab71802)

概述

  • 产品名称Anti-Ube2L3抗体- N-terminal
    参阅全部 Ube2L3 一抗
  • 描述
    兔多克隆抗体to Ube2L3 - N-terminal
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the N-terminal region of human Ube2L3 conjugated to KLH.

  • 阳性对照
    • Human breast carcinoma tissue. HL-60 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab71802 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
  • 组织特异性Ubiquitous, with highest expression in testis.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the ubiquitin-conjugating enzyme family.
  • 翻译后修饰Ubiquitinated. The alteration of UBE2L3 protein levels during the S-phase of the cell cycle is due to ubiquitin-dependent proteasomal degradation.
  • 细胞定位Nucleus. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • E2 F1 antibody
    • L UBC antibody
    • L-UBC antibody
    • UB2L3_HUMAN antibody
    • UBCE7 antibody
    • UbcH7 antibody
    • UbcM4 antibody
    • Ube2l3 antibody
    • Ubiquitin carrier protein L3 antibody
    • Ubiquitin conjugating enzyme E2 L3 antibody
    • Ubiquitin protein ligase L3 antibody
    • Ubiquitin-conjugating enzyme E2 L3 antibody
    • Ubiquitin-conjugating enzyme E2-F1 antibody
    • Ubiquitin-protein ligase L3 antibody
    see all

Anti-Ube2L3 antibody - N-terminal 图像

  • Anti-Ube2L3 antibody - N-terminal (ab71802) at 1/100 dilution + HL-60 cell lysate at 12.5 µg

    Predicted band size : 18 kDa
    Observed band size : 18 kDa
    Additional bands at : 37 kDa,45 kDa,80 kDa. We are unsure as to the identity of these extra bands.
  • ab71802 at 1/50 dilution, staining Ube2L3 in formalin-fixed, paraffin-embedded human breast carcinoma tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.

Anti-Ube2L3 antibody - N-terminal (ab71802)参考文献

ab71802 has not yet been referenced specifically in any publications.

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