概述

  • 产品名称Anti-UBE2D2抗体
    参阅全部 UBE2D2 一抗
  • 描述
    小鼠单克隆抗体to UBE2D2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment: MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWS, corresponding to amino acids 1-95 of Human UBE2D2

性能

应用

Our Abpromise guarantee covers the use of ab58248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
    • 通路Protein modification; protein ubiquitination.
    • 序列相似性Belongs to the ubiquitin-conjugating enzyme family.
    • Information by UniProt
    • 数据库链接
    • 别名
      • E2(17)KB2 antibody
      • OTTHUMP00000223475 antibody
      • OTTHUMP00000223476 antibody
      • OTTHUMP00000223477 antibody
      • OTTHUMP00000223478 antibody
      • OTTHUMP00000224375 antibody
      • PUBC 1 antibody
      • PUBC1 antibody
      • UB2D2_HUMAN antibody
      • UBC 4 antibody
      • UBC 4/5 antibody
      • UBC4 antibody
      • UBC4/5 antibody
      • UBC4/5 homolog yeast antibody
      • UBCH 5B antibody
      • UBCH5B antibody
      • UBE2D2 antibody
      • Ubiquitin carrier protein antibody
      • Ubiquitin carrier protein D2 antibody
      • Ubiquitin conjugating enzyme E2 17 kDa 2 antibody
      • Ubiquitin conjugating enzyme E2 D2 antibody
      • Ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5) antibody
      • Ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog yeast) antibody
      • Ubiquitin conjugating enzyme E2D 2 antibody
      • Ubiquitin protein ligase D2 antibody
      • Ubiquitin-conjugating enzyme E2 D2 antibody
      • Ubiquitin-conjugating enzyme E2(17)KB 2 antibody
      • Ubiquitin-conjugating enzyme E2-17 kDa 2 antibody
      • Ubiquitin-protein ligase D2 antibody
      see all

    Anti-UBE2D2 antibody 图像



    • Predicted band size : 17 kDa
      UBE2D2 antibody (ab58248) at 1ug/lane + NIH/3T3 cell lysate at 25ug/lane.

    Anti-UBE2D2 antibody (ab58248)参考文献

    ab58248 has not yet been referenced specifically in any publications.

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