概述

  • 产品名称Anti-UBCH6/UBE2E1抗体
    参阅全部 UBCH6/UBE2E1 一抗
  • 描述
    兔多克隆抗体to UBCH6/UBE2E1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 72 - 121 (KGDNIYEWRS TILGPPGSVY EGGVFFLDIT FTPEYPFKPP KVTFRTRIYH) of Human UBCH6/UBE2E1 (NP_003332)

  • 阳性对照
    • COLO205 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab90066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the ubiquitin-conjugating enzyme family.
  • 翻译后修饰ISGylation suppresses ubiquitin E2 enzyme activity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • UB2E1_HUMAN antibody
    • UbcH6 antibody
    • Ube2e1 antibody
    • Ubiquitin carrier protein E1 antibody
    • Ubiquitin conjugating enzyme E2E 1 (homologous to yeast UBC4/5) antibody
    • Ubiquitin conjugating enzyme E2E 1 antibody
    • Ubiquitin-conjugating enzyme E2 E1 antibody
    • ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) antibody
    • Ubiquitin-protein ligase E1 antibody
    see all

Anti-UBCH6/UBE2E1 antibody 图像

  • Anti-UBCH6/UBE2E1 antibody (ab90066) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 21 kDa

Anti-UBCH6/UBE2E1 antibody (ab90066)参考文献

This product has been referenced in:
  • Hoedt E  et al. SILAC-based proteomic profiling of the human MDA-MB-231 metastatic breast cancer cell line in response to the two antitumoral lactoferrin isoforms: the secreted lactoferrin and the intracellular delta-lactoferrin. PLoS One 9:e104563 (2014). WB ; Human . Read more (PubMed: 25116916) »

See 1 Publication for this product

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