概述

  • 产品名称Anti-UAP1抗体
    参阅全部 UAP1 一抗
  • 描述
    兔多克隆抗体to UAP1
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Zebrafish
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 53-473 of UAP1 isoform AGX1 (Human)

  • 阳性对照
    • H1299 lysate, A549 cells (IF), and ES-2 xenograft (IHC)

性能

应用

Our Abpromise guarantee covers the use of ab95949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
  • 组织特异性Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
  • 通路Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.
  • 序列相似性Belongs to the UDPGP type 1 family.
  • 细胞定位Cytoplasm. In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGX 1 antibody
    • AGX antibody
    • AGX-1 antibody
    • AGX-2 antibody
    • AGX1 antibody
    • Antigen X antibody
    • AntigenX antibody
    • SPAG 2 antibody
    • SPAG2 antibody
    • Sperm associated antigen 2 antibody
    • Sperm-associated antigen 2 antibody
    • UAP 1 antibody
    • uap1 antibody
    • UAP1_HUMAN antibody
    • UDP N acetylhexosamine pyrophosphorylase antibody
    • UDP N acteylglucosamine pyrophosphorylase 1 antibody
    • UDP-N-acetylglucosamine pyrophosphorylase antibody
    see all

Anti-UAP1 antibody 图像

  • Immunofluorescence analysis of paraformaldehyde fixed A549 cells using ab95949: (1) at 1/200 dilution, (2) merged with DNA probe.
  • Immunohistochemical analysis of paraffin embedded ES 2 xenograft using ab95949 at 1/500 dilution.
  • Anti-UAP1 antibody (ab95949) at 1/3000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 57 kDa

Anti-UAP1 antibody (ab95949)参考文献

ab95949 has not yet been referenced specifically in any publications.

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