概述

  • 产品名称
  • 描述
    兔多克隆抗体to UAP1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Zebrafish
  • 免疫原

    Synthetic peptide: LKDANDVPIQ CEISPLISYA GEGLEGYVAD KEFHAPLIID ENGVHELVKN , corresponding to a region within the C terminal amino acids 471-520 of Human UAP1 (NP_598567).

  • 阳性对照
    • Mouse brain lysate

性能

应用

Our Abpromise guarantee covers the use of ab113887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
  • 组织特异性
    Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
  • 通路
    Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.
  • 序列相似性
    Belongs to the UDPGP type 1 family.
  • 细胞定位
    Cytoplasm. In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGX 1 antibody
    • AGX antibody
    • AGX-1 antibody
    • AGX-2 antibody
    • AGX1 antibody
    • Antigen X antibody
    • AntigenX antibody
    • SPAG 2 antibody
    • SPAG2 antibody
    • Sperm associated antigen 2 antibody
    • Sperm-associated antigen 2 antibody
    • UAP 1 antibody
    • uap1 antibody
    • UAP1_HUMAN antibody
    • UDP N acetylhexosamine pyrophosphorylase antibody
    • UDP N acteylglucosamine pyrophosphorylase 1 antibody
    • UDP-N-acetylglucosamine pyrophosphorylase antibody
    see all

图片

  • Anti-UAP1 antibody (ab113887) at 1 µg/ml + Mouse brain lysate at 10 µg

    Predicted band size : 59 kDa

实验方案

文献

ab113887 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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