概述

  • 产品名称
    U-51605
  • 描述
    Selective PGI2 and TXA2 synthase inhibitor. PGH2 analog.
  • 生物学描述
    Selective inhibitor of PGI2 synthase (IC50 = 2 μM) and TXA2 synthase. PGH2 analog. Partial agonist at TP receptors.
  • 纯度
    > 98%

性能

文献

This product has been referenced in:
  • Li YC  et al. Structures of prostacyclin synthase and its complexes with substrate analog and inhibitor reveal a ligand-specific heme conformation change. J Biol Chem 283:2917-26 (2008). Read more (PubMed: 18032380) »
  • Gluais P  et al. In SHR aorta, calcium ionophore A-23187 releases prostacyclin and thromboxane A2 as endothelium-derived contracting factors. Am J Physiol Heart Circ Physiol 291:H2255-64 (2006). Read more (PubMed: 16798820) »
  • Zou M  et al. Prostaglandin endoperoxide-dependent vasospasm in bovine coronary arteries after nitration of prostacyclin synthase. Br J Pharmacol 126:1283-92 (1999). Read more (PubMed: 10217520) »
  • Mukhopadhyay A  et al. Effect of trimetoquinol analogs for antagonism of endoperoxide/thromboxane A2-mediated responses in human platelets and rat aorta. J Pharmacol Exp Ther 232:1-9 (1985). Read more (PubMed: 3855323) »

See 0 Publications for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab120908.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

注册