概述

  • 产品名称
  • 描述
    兔多克隆抗体to TXNRD2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human TXNRD2.

  • 阳性对照
    • This antibody gave a positive signal in the following human tissue lysates: Prostate; Liver; Testis.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab94522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

靶标

  • 功能
    Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
  • 组织特异性
    Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.
  • 序列相似性
    Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  • 细胞定位
    Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • mitochondrial antibody
    • Selenoprotein Z antibody
    • SelZ antibody
    • Thioredoxin reductase 2 antibody
    • Thioredoxin reductase 2 mitochondrial antibody
    • Thioredoxin reductase 3 antibody
    • Thioredoxin reductase beta antibody
    • Thioredoxin reductase TR3 antibody
    • TR 3 antibody
    • TR antibody
    • TR beta antibody
    • TR-beta antibody
    • TR3 antibody
    • TRXR 2 antibody
    • TRXR2 antibody
    • TRXR2_HUMAN antibody
    • TXNRD 2 antibody
    • Txnrd2 antibody
    see all

图片

  • All lanes : Anti-TXNRD2 antibody (ab94522) at 1 µg/ml

    Lane 1 : Human prostate tissue lysate (cirrhosis) - total protein (ab30307)
    Lane 2 : Human liver tissue lysate - total protein (ab29889)
    Lane 3 : Human testis tissue lysate - total protein (ab30257)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 56 kDa
    Observed band size : 56 kDa
    Additional bands at : 120 kDa,40 kDa,53 kDa (possible isoform). We are unsure as to the identity of these extra bands.

    Exposure time : 30 seconds

实验方案

文献

ab94522 has not yet been referenced specifically in any publications.

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