概述

  • 产品名称Anti-TXNL2抗体
    参阅全部 TXNL2 一抗
  • 描述
    小鼠单克隆抗体to TXNL2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-336 of Human TXNL2

性能

应用

Our Abpromise guarantee covers the use of ab56686 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
    • 组织特异性Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine.
    • 序列相似性Contains 2 glutaredoxin domains.
      Contains 1 thioredoxin domain.
    • 结构域The thioredoxin domain lacks the two redox-active cysteines. This strongly suggests that it lacks thioredoxin activity.
    • 细胞定位Cytoplasm > cell cortex. Cytoplasm > myofibril > sarcomere > Z line. Under the plasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area. In the Z line, found associated with CSRP3.
    • Information by UniProt
    • 数据库链接
    • 别名
      • glrx3 antibody
      • GLRX3_HUMAN antibody
      • GLRX4 antibody
      • Glutaredoxin 3 antibody
      • Glutaredoxin 4 antibody
      • Glutaredoxin-3 antibody
      • GRX3 antibody
      • GRX4 antibody
      • PICOT antibody
      • PKC interacting cousin of thioredoxin antibody
      • PKC theta interacting protein antibody
      • PKC-interacting cousin of thioredoxin antibody
      • PKC-theta-interacting protein antibody
      • PKCq interacting protein antibody
      • PKCq-interacting protein antibody
      • Thioredoxin like protein 2 antibody
      • Thioredoxin-like protein 2 antibody
      • TXNL3 antibody
      see all

    Anti-TXNL2 antibody 图像



    • Predicted band size : 37 kDa
      TXNL2 antibody (ab56686) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-TXNL2 antibody (ab56686)参考文献

    ab56686 has not yet been referenced specifically in any publications.

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