概述

  • 产品名称Anti-TXNL2抗体
    参阅全部 TXNL2 一抗
  • 描述
    兔多克隆抗体to TXNL2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment containing a sequence corresponding to a region within amino acids 45 and 211 of Human TXNL2 (AAH05289).

  • 阳性对照
    • 293T, A431 and Raji cell lysates.

性能

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应用

Our Abpromise guarantee covers the use of ab102472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 37 kDa.

靶标

  • 功能Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
  • 组织特异性Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine.
  • 序列相似性Contains 2 glutaredoxin domains.
    Contains 1 thioredoxin domain.
  • 结构域The thioredoxin domain lacks the two redox-active cysteines. This strongly suggests that it lacks thioredoxin activity.
  • 细胞定位Cytoplasm > cell cortex. Cytoplasm > myofibril > sarcomere > Z line. Under the plasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area. In the Z line, found associated with CSRP3.
  • Information by UniProt
  • 数据库链接
  • 别名
    • glrx3 antibody
    • GLRX3_HUMAN antibody
    • GLRX4 antibody
    • Glutaredoxin 3 antibody
    • Glutaredoxin 4 antibody
    • Glutaredoxin-3 antibody
    • GRX3 antibody
    • GRX4 antibody
    • PICOT antibody
    • PKC interacting cousin of thioredoxin antibody
    • PKC theta interacting protein antibody
    • PKC-interacting cousin of thioredoxin antibody
    • PKC-theta-interacting protein antibody
    • PKCq interacting protein antibody
    • PKCq-interacting protein antibody
    • Thioredoxin like protein 2 antibody
    • Thioredoxin-like protein 2 antibody
    • TXNL3 antibody
    see all

Anti-TXNL2 antibody 图像

  • Anti-TXNL2 antibody (ab102472) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 37 kDa

Anti-TXNL2 antibody (ab102472)参考文献

ab102472 has not yet been referenced specifically in any publications.

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