概述

  • 产品名称Anti-TXNDC2抗体
  • 描述
    兔多克隆抗体to TXNDC2
  • 经测试应用适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: corresponding to N terminal amino acids 5-114 of Human TXNDC2.

  • 阳性对照
    • Human testis tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab121579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.
IHC-P 1/750. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. Use buffer at pH 6 for antigen retrieval.

靶标

  • 功能Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
  • 组织特异性Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.
  • 序列相似性Contains 1 thioredoxin domain.
  • 细胞定位Cytoplasm. In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
  • Information by UniProt
  • 数据库链接
  • 别名
    • sperm-specific thioredoxin 1 antibody
    • Spermatid-specific thioredoxin-1 antibody
    • SPTRX antibody
    • Sptrx-1 antibody
    • SPTRX1 antibody
    • Thioredoxin domain containing 2 (spermatozoa) antibody
    • Thioredoxin domain-containing protein 2 antibody
    • TXND2_HUMAN antibody
    • Txndc2 antibody
    see all

Anti-TXNDC2 antibody 图像

  • ab121579, at a 1/750 dilution, staining TXNDC2 in paraffin-embedded Human testis by immunohistochemistry.

Anti-TXNDC2 antibody (ab121579)参考文献

ab121579 has not yet been referenced specifically in any publications.

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