概述

  • 产品名称Anti-TXNDC17抗体
  • 描述
    兔多克隆抗体to TXNDC17
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence, corresponding to amino acids 1-62 (MARYEEVSVS GFEEFHRAVE QHNGKTIFAY FTGSKDAGGK SWCPDCVQAE PVVREGLKHI SE) of Human TXNDC17.

  • 阳性对照
    • Human cerebellum tissue; RT4, U251 MG cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab121725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

靶标

  • 功能Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
  • 组织特异性Ubiquitously expressed in cell lines.
  • 序列相似性Belongs to the thioredoxin family.
    Contains 1 thioredoxin domain.
  • 翻译后修饰The oxidized protein is reduced by TRXR1.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 14 kDa thioredoxin-related protein antibody
    • Protein 42-9-9 antibody
    • Thioredoxin domain-containing protein 17 antibody
    • Thioredoxin-like protein 5 antibody
    • TRP14 antibody
    • TXD17_HUMAN antibody
    • TXNDC17 antibody
    see all

Anti-TXNDC17 antibody 图像

  • ab121725 at 1/500 dilution staining TXNDC17 in Paraffin-embedded Human cerebellum tissue by Immunohistochemistry.
  • All lanes : Anti-TXNDC17 antibody (ab121725) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U251 MG cell lysate
    Lane 3 : Human plasma
    Lane 4 : Human Liver tissue lysate
    Lane 5 : Human Tonsil tissue lysate

    Developed using the ECL technique

Anti-TXNDC17 antibody (ab121725)参考文献

ab121725 has not yet been referenced specifically in any publications.

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