概述

  • 产品名称Anti-TWEAK抗体
    参阅全部 TWEAK 一抗
  • 描述
    小鼠单克隆抗体to TWEAK
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: SLSAQEPAQE ELVAEEDQDP SELNPQTEES QDPAPFLNRL VRPRRSAPKG RKTRARRAIA AHYEVHPRPG QDGAQADGGY TTCLRP, corresponding to amino acids 49-135 of Human TWEAK

性能

应用

Our Abpromise guarantee covers the use of ab57926 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
    • 组织特异性Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.
    • 序列相似性Belongs to the tumor necrosis factor family.
    • 翻译后修饰The soluble form derives from the membrane form by proteolytic processing.
    • 细胞定位Secreted and Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • APO 3 ligand antibody
      • APO 3L antibody
      • APO3 ligand antibody
      • APO3/DR3 ligand antibody
      • APO3L antibody
      • DR3LG antibody
      • MGC129581 antibody
      • MGC20669 antibody
      • secreted form antibody
      • TNF-related weak inducer of apoptosis antibody
      • TNF12_HUMAN antibody
      • TNFSF 12 antibody
      • Tnfsf12 antibody
      • TNFSF12 protein antibody
      • Tumor necrosis factor (ligand) superfamily member 12 antibody
      • Tumor necrosis factor ligand superfamily member 12 antibody
      • Tumor necrosis factor superfamily member 12 antibody
      • TWEAK antibody
      • UNQ181/PRO207 antibody
      see all

    Anti-TWEAK antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57926 TWEAK antibody at 1ug/ml. Predicted band size of immunogen is 33 kDa

    Anti-TWEAK antibody (ab57926)参考文献

    ab57926 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"