Anti-Tumor necrosis factor alpha-induced protein 8-like protein 2抗体(ab110389)

概述

  • 产品名称Anti-Tumor necrosis factor alpha-induced protein 8-like protein 2抗体
    参阅全部 Tumor necrosis factor alpha-induced protein 8-like protein 2 一抗
  • 描述
    兔多克隆抗体to Tumor necrosis factor alpha-induced protein 8-like protein 2
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    A synthesized peptide derived from an internal region of Human Tumor necrosis factor alpha-induced protein 8-like protein 2.

  • 阳性对照
    • Extracts from HuvEc cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol, 0.88% Sodium chloride
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab110389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 21 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. or using a pressure cooker for about 5 minutes.

靶标

  • 功能Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.
  • 序列相似性Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
  • 结构域The central region was initially thought to constitute a DED (death effector) domain. However, 3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED (death effector) domain. It consists of a large, hydrophobic central cavity that is poised for cofactor binding.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AW610835 antibody
    • FLJ23467 antibody
    • Inflammation factor 20 antibody
    • Inflammation factor protein 20 antibody
    • TIPE2 antibody
    • TNF alpha-induced protein 8-like protein 2 antibody
    • TNFAIP8-like protein 2 antibody
    • TNFAIP8L2 antibody
    • TP8L2_HUMAN antibody
    • Tumor necrosis factor alpha induced protein 8 like 2 antibody
    • Tumor necrosis factor alpha-induced protein 8-like protein 2 antibody
    see all

Anti-Tumor necrosis factor alpha-induced protein 8-like protein 2 antibody 图像

  • All lanes : Anti-Tumor necrosis factor alpha-induced protein 8-like protein 2 antibody (ab110389) at 1/500 dilution

    Lane 1 : extracts from HuvEc cells
    Lane 2 : extracts from HuvEc cells with blocking peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 21 kDa

Anti-Tumor necrosis factor alpha-induced protein 8-like protein 2 antibody (ab110389)参考文献

ab110389 has not yet been referenced specifically in any publications.

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