Anti-TUFM抗体(ab67991)
Key features and details
- Mouse polyclonal to TUFM
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-TUFM抗体
参阅全部 TUFM 一抗 -
描述
小鼠多克隆抗体to TUFM -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
Recombinant full length protein within Human TUFM aa 1-500. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- Brain tissue lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab67991于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
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说明 |
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WB
1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa). |
靶标
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功能
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. -
疾病相关
Combined oxidative phosphorylation deficiency 4 (COXPD4) [MIM:610678]: A mitochondrial disease resulting in neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes. Note=The disease is caused by mutations affecting the gene represented in this entry. -
序列相似性
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. -
细胞定位
Mitochondrion. - Information by UniProt
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数据库链接
- Entrez Gene: 293481 Rat
- SwissProt: P85834 Rat
- Unigene: 48850 Rat
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别名
- COXPD4 antibody
- EF Tu antibody
- EF TuMT antibody
see all
图片
数据表及文件
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Datasheet download
文献 (5)
ab67991 被引用在 5 文献中.
- Kim SJ et al. GRSF1 is an age-related regulator of senescence. Sci Rep 9:5546 (2019). PubMed: 30944385
- Lee DE et al. Mitochondrial mRNA translation initiation contributes to oxidative metabolism in the myocardia of aged, obese mice. Exp Gerontol 121:62-70 (2019). PubMed: 30928679
- Lee DE et al. Translational machinery of mitochondrial mRNA is promoted by physical activity in Western diet-induced obese mice. Acta Physiol (Oxf) 218:167-177 (2016). PubMed: 27061106
- Lei Y et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity 36:933-46 (2012). PubMed: 22749352
- Warren CM et al. Sub-proteomic fractionation, iTRAQ, and OFFGEL-LC-MS/MS approaches to cardiac proteomics. J Proteomics 73:1551-61 (2010). WB ; Rat . PubMed: 20394843