Anti-Tubulin Polymerization Promoting Protein抗体[EPR3315] (ab119987)


  • 产品名称Anti-Tubulin Polymerization Promoting Protein抗体[EPR3315]
    参阅全部 Tubulin Polymerization Promoting Protein 一抗
  • 描述
    兔单克隆抗体[EPR3315] to Tubulin Polymerization Promoting Protein
  • 经测试应用适用于: WB, IHC-P, IPmore details
    不适用于: Flow Cyt or ICC
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to residues in Human Tubulin Polymerization Promoting Protein.

  • 阳性对照
    • Human fetal brain and SH-SY5Y cell lysates; Human astrocytoma tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab119987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 25 kDa (predicted molecular weight: 23 kDa).
IHC-P 1/100 - 1/250. Antigen retrieval is recommended. Heat up to 98 °C, below boiling, and then let cool for 10-20 min.
IP 1/10 - 1/100.
  • 应用说明Is unsuitable for Flow Cyt or ICC.
  • 靶标

    • 功能May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
    • 组织特异性Widely expressed.
    • 序列相似性Belongs to the TPPP family.
    • 翻译后修饰Poor substrate for GSK3 (By similarity). Phosphorylated by LIMK1 on serine residues. Phosphorylation may alter the tubulin polymerization activity.
    • 细胞定位Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 25 kDa brain specific protein antibody
      • 25 kDa brain-specific protein antibody
      • Brain specific protein p25 alpha antibody
      • Glycogen synthase kinase 3 (GSK3) inhibitor p24 antibody
      • OTTHUMP00000161630 antibody
      • p24 antibody
      • p25 antibody
      • p25-alpha antibody
      • p25alpha antibody
      • TPPP antibody
      • TPPP/p25 antibody
      • TPPP_HUMAN antibody
      • TPPP1 antibody
      • Tubulin polymerization promoting protein antibody
      • Tubulin polymerization-promoting protein antibody
      see all

    Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] 图像

    • All lanes : Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] (ab119987) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : SH-SY5Y cell lysate

      Lysates/proteins at 10 µg per lane.

      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 23 kDa
    • ab119987 at 1/100 dilution staining Tubulin Polymerization Promoting Protein in Paraffin-embedded Human astrocytoma tissue by Immunohistochemistry.

    Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] (ab119987)参考文献

    ab119987 has not yet been referenced specifically in any publications.

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