Anti-Tubulin Polymerization Promoting Protein抗体(ab48731)

概述

  • 产品名称Anti-Tubulin Polymerization Promoting Protein抗体
    参阅全部 Tubulin Polymerization Promoting Protein 一抗
  • 描述
    兔多克隆抗体to Tubulin Polymerization Promoting Protein
  • 特异性This antibody recognizes 2900041A09Rik
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Chicken, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide: FTGSHKERFD QSGKGKGKAG RVDLVDESGY VPGYKHAGTY DQKVQGGK, corresponding to C terminal amino acids 171-218 of Mouse Tubulin Polymerization Promoting Protein

  • 阳性对照
    • Brain lysate

性能

应用

Our Abpromise guarantee covers the use of ab48731 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the TPPP family.
  • 翻译后修饰Poor substrate for GSK3 (By similarity). Phosphorylated by LIMK1 on serine residues. Phosphorylation may alter the tubulin polymerization activity.
  • 细胞定位Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 25 kDa brain specific protein antibody
    • 25 kDa brain-specific protein antibody
    • Brain specific protein p25 alpha antibody
    • Glycogen synthase kinase 3 (GSK3) inhibitor p24 antibody
    • OTTHUMP00000161630 antibody
    • p24 antibody
    • p25 antibody
    • p25-alpha antibody
    • p25alpha antibody
    • TPPP antibody
    • TPPP/p25 antibody
    • TPPP_HUMAN antibody
    • TPPP1 antibody
    • Tubulin polymerization promoting protein antibody
    • Tubulin polymerization-promoting protein antibody
    see all

Anti-Tubulin Polymerization Promoting Protein antibody 图像

  • Anti-Tubulin Polymerization Promoting Protein antibody (ab48731) at 1.25 µg/ml + Brain lysate at 10 µg with 5% skimmed milk in PBS

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 24 kDa
    Observed band size : 24 kDa

Anti-Tubulin Polymerization Promoting Protein antibody (ab48731)参考文献

ab48731 has not yet been referenced specifically in any publications.

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