Anti-Tubulin Polymerization Promoting Protein抗体(ab117948)

概述

  • 产品名称Anti-Tubulin Polymerization Promoting Protein抗体
    参阅全部 Tubulin Polymerization Promoting Protein 一抗
  • 描述
    兔多克隆抗体to Tubulin Polymerization Promoting Protein
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chicken, Guinea pig, Cat, Dog
  • 免疫原

    Synthetic peptide, corresponding to a region within N terminal amino acids 17-66 (KSPGDPSKDR AAKRLSLESE GAGEGAAASP ELSALEEAFR RFAVHGDARA) of Human Tubulin Polymerization Promoting Protein (NP_008961).

  • 阳性对照
    • Human fetal liver lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab117948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the TPPP family.
  • 翻译后修饰Poor substrate for GSK3 (By similarity). Phosphorylated by LIMK1 on serine residues. Phosphorylation may alter the tubulin polymerization activity.
  • 细胞定位Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 25 kDa brain specific protein antibody
    • 25 kDa brain-specific protein antibody
    • Brain specific protein p25 alpha antibody
    • Glycogen synthase kinase 3 (GSK3) inhibitor p24 antibody
    • OTTHUMP00000161630 antibody
    • p24 antibody
    • p25 antibody
    • p25-alpha antibody
    • p25alpha antibody
    • TPPP antibody
    • TPPP/p25 antibody
    • TPPP_HUMAN antibody
    • TPPP1 antibody
    • Tubulin polymerization promoting protein antibody
    • Tubulin polymerization-promoting protein antibody
    see all

Anti-Tubulin Polymerization Promoting Protein antibody 图像

  • Anti-Tubulin Polymerization Promoting Protein antibody (ab117948) at 1 µg/ml + Human fetal liver lysate at 10 µg

    Predicted band size : 23 kDa

Anti-Tubulin Polymerization Promoting Protein antibody (ab117948)参考文献

ab117948 has not yet been referenced specifically in any publications.

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