Anti-TTF1抗体[8G7G3/1], prediluted (ab82743)

概述

  • 产品名称Anti-TTF1抗体[8G7G3/1], prediluted
    参阅全部 TTF1 一抗
  • 描述
    小鼠单克隆抗体[8G7G3/1] to TTF1, prediluted
  • 特异性ab82743 does not stain colon and breast carcinoma tissues.
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Recombinant rat TTF1 protein.

  • 阳性对照
    • Primary lung adenocarcinoma, small cell carcinoma and thyroid tissues.

性能

  • 形式Prediluted
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, Stabilizing agent, pH 7.5
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号8G7G3/1
  • 同种型IgG1
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab82743 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
IHC-Fr
  • 应用说明IHC-P: Use neat for 30 minutes at room temperature.
    Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 prior to immunostaining.
    IHC-Fr (acetone-fixed): Use neat for 30 minutes at room temperature.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis.
    • 组织特异性Thyroid and lung.
    • 疾病相关Defects in NKX2-1 are the cause of benign hereditary chorea (BHC) [MIM:118700]; also known as hereditary chorea without dementia. BHC is an autosomal dominant movement disorder. The early onset of symptoms (usully before the age of 5) and the observation that in some BHC families the symptoms tend to decrease in adulthood suggests that the disorder results from a developmental disturbance of the brain. BHC is non-progressive and patients have normal or slightly below normal intelligence. There is considerable inter- and intrafamilial variability, including dysarthria, axial distonia and gait disturbances.
      Defects in NKX2-1 are the cause of choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD) [MIM:610978]. This syndrome include neurological, thyroid, and respiratory problems.
    • 序列相似性Belongs to the NK-2 homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • 翻译后修饰Phosphorylated on serine residues.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AV026640 antibody
      • BCH antibody
      • Benign chorea antibody
      • BHC antibody
      • Homeobox protein NK 2 homolog A antibody
      • Homeobox protein NK-2 homolog A antibody
      • Homeobox protein Nkx 2.1 antibody
      • Homeobox protein Nkx-2.1 antibody
      • Homeobox protein Nkx2.1 antibody
      • NK 2 antibody
      • NK 2 homolog A antibody
      • NK2 antibody
      • NK2 homeobox 1 antibody
      • NK2, drosophila, homolog of, A antibody
      • NK2.1, mouse, homolog of antibody
      • Nkx 2 1 antibody
      • NKX 2.1 antibody
      • NKX 2A antibody
      • NKX2 1 antibody
      • Nkx2-1 antibody
      • NKX2.1 antibody
      • NKX21_HUMAN antibody
      • NKX2A antibody
      • T EBP antibody
      • T/EBP antibody
      • TEBP antibody
      • Thyroid nuclear factor 1 antibody
      • Thyroid nuclear factor antibody
      • Thyroid specific enhancer binding protein antibody
      • Thyroid transcription factor 1 antibody
      • Tin man antibody
      • Tinman antibody
      • TITF 1 antibody
      • TITF1 antibody
      • TTF 1 antibody
      • TTF-1 antibody
      • TTF1 antibody
      see all

    Anti-TTF1 antibody [8G7G3/1], prediluted 图像

    • ab82743 staining TTF1 in human lung tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections).

    Anti-TTF1 antibody [8G7G3/1], prediluted (ab82743)参考文献

    This product has been referenced in:
    • Holzinger A  et al. Monoclonal antibody to thyroid transcription factor-1: production, characterization, and usefulness in tumor diagnosis. Hybridoma 15:49-53 (1996). Read more (PubMed: 9064286) »

    See 1 Publication for this product

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